Journal of Stroke

Review

May 30, 2024

Leukoaraiosis: Epidemiology, Imaging, Risk Factors, and Management of Age-Related Cerebral White Matter Hyperintensities

Wen-Qing Huang, Qing Lin, Chi-Meng Tzeng

J Stroke. 2024;26(2):131-163.

Leukoaraiosis (LA) manifests as cerebral white matter hyperintensities on T2-weighted magnetic resonance imaging scans and corresponds to white matter lesions or abnormalities in brain tissue. Clinically, it is generally detected...

Review

May 30, 2024

Cancer-Associated Stroke: Thrombosis Mechanism, Diagnosis, Outcome, and Therapeutic Strategies

Ji Hoe Heo, Jaeseob Yun, Kwang Hyun Kim, Jae Wook Jung, Joonsang Yoo, Young Dae Kim, Hyo Suk Nam

J Stroke. 2024;26(2):164-178.

Cancer can induce hypercoagulability, which may lead to stroke. This occurs when tumor cells activate platelets as part of their growth and metastasis. Tumor cells activate platelets by generating thrombin...

Review

May 30, 2024

Prevalence of Cerebral Amyloid Angiopathy Pathology and Strictly Lobar Microbleeds in East-Asian Versus Western Populations: A Systematic Review and Meta-Analysis

Anna M. De Kort, Marcel M. Verbeek, Floris H.B.M. Schreuder, Catharina J.M. Klijn, Lieke Jäkel

J Stroke. 2024;26(2):179-189.

Background and Purpose Possible differences in the prevalence of cerebral amyloid angiopathy (CAA) in East-Asian compared to Western populations have received little attention, and results so far have been ambiguous....

Review

May 30, 2024

Distal Medium Vessel Occlusion Strokes: Understanding the Present and Paving the Way for a Better Future

Raul G. Nogueira, Mohamed F. Doheim, Alhamza R. Al-Bayati, Jin Soo Lee, Diogo C. Haussen, Mahmoud Mohammaden, Michael Lang, Matthew Starr, Marcelo Rocha, Catarina Perry da Câmara, et al.

J Stroke. 2024;26(2):190-202.

Distal medium vessel occlusions (DMVOs) are thought to cause as many as 25% to 40% of all acute ischemic strokes and may result in substantial disability amongst survivors. Although intravenous...

Review

May 30, 2024

Neuroprotective Approaches for Brain Injury After Cardiac Arrest: Current Trends and Prospective Avenues

Subash Marasini, Xiaofeng Jia

J Stroke. 2024;26(2):203-230.

With the implementation of improved bystander cardiopulmonary resuscitation techniques and public-access defibrillation, survival after out-of-hospital cardiac arrest (OHCA) has increased significantly over the years. Nevertheless, OHCA survivors have residual anoxia/reperfusion...

Original Article

May 30, 2024

The Influence of Non-High-Density Lipoprotein Cholesterol on the Efficacy of Genotype-Guided Dual Antiplatelet Therapy in Preventing Stroke Recurrence

Qin Xu, Xia Meng, Hao Li, Xuewei Xie, Jing Jing, Jinxi Lin, Yong Jiang, Yilong Wang, Xingquan Zhao, Zixiao Li, et al.

J Stroke. 2024;26(2):231-241.

Background and Purpose Non-high-density lipoprotein cholesterol (non-HDL-C), which represents the total cholesterol content of all pro-atherogenic lipoproteins, has recently been included as a new target for lipid-lowering therapy in high-risk...

Original Article

May 30, 2024

Device Closure or Antithrombotic Therapy After Cryptogenic Stroke in Elderly Patients With a High-Risk Patent Foramen Ovale

Pil Hyung Lee, Jung-Sun Kim, Jae-Kwan Song, Sun U. Kwon, Bum Joon Kim, Ji Sung Lee, Byung Joo Sun, Jong Shin Woo, Soe Hee Ann, Jung-Won Suh, et al.

J Stroke. 2024;26(2):242-251.

Background and Purpose In young patients (aged 18–60 years) with patent foramen ovale (PFO)- associated stroke, percutaneous closure has been found to be useful for preventing recurrent ischemic stroke or...

Original Article

May 30, 2024

How Do Quantitative Tissue Imaging Outcomes in Acute Ischemic Stroke Relate to Clinical Outcomes?

Johanna M. Ospel, Leon Rinkel, Aravind Ganesh, Andrew Demchuk, Manraj Heran, Eric Sauvageau, Manish Joshi, Diogo Haussen, Mahesh Jayaraman, Shelagh Coutts, et al.

J Stroke. 2024;26(2):252-259.

Background and Purpose Infarct volume and other imaging markers are increasingly used as surrogate measures for clinical outcome in acute ischemic stroke research, but how improvements in these imaging surrogates...

Original Article

May 30, 2024

Infarcts Due to Large Vessel Occlusions Continue to Grow Despite Near-Complete Reperfusion After Endovascular Treatment

Johanna M. Ospel, Nathaniel Rex, Karim Oueidat, Rosalie McDonough, Leon Rinkel, Grayson Baird, Scott Collins, Gaurav Jindal, Matthew D. Alvin, Jerrold Boxerman, et al.

J Stroke. 2024;26(2):260-268.

Background and Purpose Infarcts in acute ischemic stroke (AIS) patients may continue to grow even after reperfusion, due to mechanisms such as microvascular obstruction and reperfusion injury. We investigated whether...

Original Article

May 30, 2024

Endovascular Therapy in the Extended Time Window for Large Vessel Occlusion in Patients With Pre-Stroke Disability

Kanta Tanaka, Hiroshi Yamagami, Muhammad M. Qureshi, Kazutaka Uchida, James E. Siegler, Raul G. Nogueira, Shinichi Yoshimura, Nobuyuki Sakai, Nicolas Martinez-Majander, Simon Nagel, et al.

J Stroke. 2024;26(2):269-279.

Background and Purpose We compared the outcomes of endovascular therapy (EVT) in an extended time window in patients with large-vessel occlusion (LVO) between patients with and without pre-stroke disability. Methods In...

Original Article

May 30, 2024

Tenecteplase Versus Alteplase in Medium Vessel Occlusion Ischemic Stroke: A Secondary Analysis of the Alteplase Compared to Tenecteplase Randomized Trial

Fouzi Bala, Nishita Singh, Katrina Ignacio, Ibrahim Alhabli, Ayoola Ademola, Anas Alrohimi, Houman Khosravani, Aleksander Tkach, Luciana Catanese, Dariush Dowlatshahi, et al.

J Stroke. 2024;26(2):280-289.

Background and Purpose The safety and efficacy of tenecteplase in patients with ischemic stroke due to medium vessel occlusion (MeVO) are not well studied. We aimed to compare tenecteplase with...

Original Article

May 30, 2024

Endovascular Thrombectomy Versus Intravenous Thrombolysis of Posterior Cerebral Artery Occlusion Stroke

Silja Räty, Thanh N. Nguyen, Simon Nagel, Davide Strambo, Patrik Michel, Christian Herweh, Muhammad M. Qureshi, Mohamad Abdalkader, Pekka Virtanen, Marta Olive-Gadea, et al.

J Stroke. 2024;26(2):290-299.

Background and Purpose Posterior cerebral artery occlusion (PCAo) can cause long-term disability, yet randomized controlled trials to guide optimal reperfusion strategy are lacking. We compared the outcomes of PCAo patients...

Original Article

May 30, 2024

Deep Learning-Based Automatic Classification of Ischemic Stroke Subtype Using Diffusion-Weighted Images

Wi-Sun Ryu, Dawid Schellingerhout, Hoyoun Lee, Keon-Joo Lee, Chi Kyung Kim, Beom Joon Kim, Jong-Won Chung, Jae-Sung Lim, Joon-Tae Kim, Dae-Hyun Kim, et al.

J Stroke. 2024;26(2):300-311.

Background and Purpose Accurate classification of ischemic stroke subtype is important for effective secondary prevention of stroke. We used diffusion-weighted image (DWI) and atrial fibrillation (AF) data to train a...

Original Article

May 30, 2024

A Multimodal Ensemble Deep Learning Model for Functional Outcome Prognosis of Stroke Patients

Hye-Soo Jung, Eun-Jae Lee, Dae-Il Chang, Han Jin Cho, Jun Lee, Jae-Kwan Cha, Man-Seok Park, Kyung Ho Yu, Jin-Man Jung, Seong Hwan Ahn, et al.

J Stroke. 2024;26(2):312-320.

Background and Purpose The accurate prediction of functional outcomes in patients with acute ischemic stroke (AIS) is crucial for informed clinical decision-making and optimal resource utilization. As such, this study...

Leukoaraiosis: Epidemiology, Imaging, Risk Factors, and Management of Age-Related Cerebral White Matter Hyperintensities Wen-Qing Huang, Qing Lin, Chi-Meng Tzeng J Stroke. 2024;26(2):131-163. Review May 30, 2024 PDF	Cancer-Associated Stroke: Thrombosis Mechanism, Diagnosis, Outcome, and Therapeutic Strategies Ji Hoe Heo, Jaeseob Yun, Kwang Hyun Kim, Jae Wook Jung, Joonsang Yoo, Young Dae Kim, Hyo Suk Nam J Stroke. 2024;26(2):164-178. Review May 30, 2024 PDF
Prevalence of Cerebral Amyloid Angiopathy Pathology and Strictly Lobar Microbleeds in East-Asian Versus Western Populations: A Systematic Review and Meta-Analysis Anna M. De Kort, Marcel M. Verbeek, Floris H.B.M. Schreuder, Catharina J.M. Klijn, Lieke Jäkel J Stroke. 2024;26(2):179-189. Review May 30, 2024 PDF	Distal Medium Vessel Occlusion Strokes: Understanding the Present and Paving the Way for a Better Future Raul G. Nogueira, Mohamed F. Doheim, Alhamza R. Al-Bayati, Jin Soo Lee, Diogo C. Haussen, Mahmoud Mohammaden, Michael Lang, Matthew Starr, Marcelo Rocha, Catarina Perry da Câmara, et al. J Stroke. 2024;26(2):190-202. Review May 30, 2024 PDF
Neuroprotective Approaches for Brain Injury After Cardiac Arrest: Current Trends and Prospective Avenues Subash Marasini, Xiaofeng Jia J Stroke. 2024;26(2):203-230. Review May 30, 2024 PDF	The Influence of Non-High-Density Lipoprotein Cholesterol on the Efficacy of Genotype-Guided Dual Antiplatelet Therapy in Preventing Stroke Recurrence Qin Xu, Xia Meng, Hao Li, Xuewei Xie, Jing Jing, Jinxi Lin, Yong Jiang, Yilong Wang, Xingquan Zhao, Zixiao Li, et al. J Stroke. 2024;26(2):231-241. Original Article May 30, 2024 PDF
Device Closure or Antithrombotic Therapy After Cryptogenic Stroke in Elderly Patients With a High-Risk Patent Foramen Ovale Pil Hyung Lee, Jung-Sun Kim, Jae-Kwan Song, Sun U. Kwon, Bum Joon Kim, Ji Sung Lee, Byung Joo Sun, Jong Shin Woo, Soe Hee Ann, Jung-Won Suh, et al. J Stroke. 2024;26(2):242-251. Original Article May 30, 2024 PDF	How Do Quantitative Tissue Imaging Outcomes in Acute Ischemic Stroke Relate to Clinical Outcomes? Johanna M. Ospel, Leon Rinkel, Aravind Ganesh, Andrew Demchuk, Manraj Heran, Eric Sauvageau, Manish Joshi, Diogo Haussen, Mahesh Jayaraman, Shelagh Coutts, et al. J Stroke. 2024;26(2):252-259. Original Article May 30, 2024 PDF
Infarcts Due to Large Vessel Occlusions Continue to Grow Despite Near-Complete Reperfusion After Endovascular Treatment Johanna M. Ospel, Nathaniel Rex, Karim Oueidat, Rosalie McDonough, Leon Rinkel, Grayson Baird, Scott Collins, Gaurav Jindal, Matthew D. Alvin, Jerrold Boxerman, et al. J Stroke. 2024;26(2):260-268. Original Article May 30, 2024 PDF	Endovascular Therapy in the Extended Time Window for Large Vessel Occlusion in Patients With Pre-Stroke Disability Kanta Tanaka, Hiroshi Yamagami, Muhammad M. Qureshi, Kazutaka Uchida, James E. Siegler, Raul G. Nogueira, Shinichi Yoshimura, Nobuyuki Sakai, Nicolas Martinez-Majander, Simon Nagel, et al. J Stroke. 2024;26(2):269-279. Original Article May 30, 2024 PDF
Tenecteplase Versus Alteplase in Medium Vessel Occlusion Ischemic Stroke: A Secondary Analysis of the Alteplase Compared to Tenecteplase Randomized Trial Fouzi Bala, Nishita Singh, Katrina Ignacio, Ibrahim Alhabli, Ayoola Ademola, Anas Alrohimi, Houman Khosravani, Aleksander Tkach, Luciana Catanese, Dariush Dowlatshahi, et al. J Stroke. 2024;26(2):280-289. Original Article May 30, 2024 PDF	Endovascular Thrombectomy Versus Intravenous Thrombolysis of Posterior Cerebral Artery Occlusion Stroke Silja Räty, Thanh N. Nguyen, Simon Nagel, Davide Strambo, Patrik Michel, Christian Herweh, Muhammad M. Qureshi, Mohamad Abdalkader, Pekka Virtanen, Marta Olive-Gadea, et al. J Stroke. 2024;26(2):290-299. Original Article May 30, 2024 PDF
Deep Learning-Based Automatic Classification of Ischemic Stroke Subtype Using Diffusion-Weighted Images Wi-Sun Ryu, Dawid Schellingerhout, Hoyoun Lee, Keon-Joo Lee, Chi Kyung Kim, Beom Joon Kim, Jong-Won Chung, Jae-Sung Lim, Joon-Tae Kim, Dae-Hyun Kim, et al. J Stroke. 2024;26(2):300-311. Original Article May 30, 2024 PDF	A Multimodal Ensemble Deep Learning Model for Functional Outcome Prognosis of Stroke Patients Hye-Soo Jung, Eun-Jae Lee, Dae-Il Chang, Han Jin Cho, Jun Lee, Jae-Kwan Cha, Man-Seok Park, Kyung Ho Yu, Jin-Man Jung, Seong Hwan Ahn, et al. J Stroke. 2024;26(2):312-320. Original Article May 30, 2024 PDF
Pupillometer-Based Neurological Pupil Index Differential: A Potential Predictor of Post-Stroke Delirium Kotaro Noda, Tomotaka Tanaka, Soichiro Abe, Ryo Usui, Misa Matsumoto, Yoshito Arakaki, Hiroyuki Kida, Ryoma Inui, Kaoru Kohama, Kazuo Washida, et al. J Stroke. 2024;26(2):321-324. Letter to the Editor May 30, 2024 PDF	Prevalence and Associations of Dural Arteriovenous Fistulae in Cerebral Venous Thrombosis: Analysis of ACTION-CVT Aaron Shoskes, Liqi Shu, Thanh N. Nguyen, Mohamad Abdalkader, James Giles, Jordan Amar, James E. Siegler, Nils Henninger, Marwa ElNazeir, Sami Al Kasab, et al. J Stroke. 2024;26(2):325-329. Letter to the Editor May 30, 2024 PDF
The Role of Atrial Cardiopathy as a Potential Cause of Embolic Stroke of Undetermined Source Angelo Cascio Rizzo, Ghil Schwarz, Andrea Bonelli, Andrea Di Pietro, Martina Di Pietro, Francesco Aruta, Cristina Motto, Benedetta De Chiara, Antonella Moreo, Elio Clemente Agostoni J Stroke. 2024;26(2):330-334. Letter to the Editor May 30, 2024 PDF	Left Atrial Mechanical Dysfunction Is Associated With Atrial Fibrillation and Recurrent Stroke After Cryptogenic Stroke Joseph Raco, Ravi Shah, Michael Farbaniec, Faye L. Norby, Megan Mann, Mario D. Gonzalez, Gerald V. Naccarelli, Ankit Maheshwari J Stroke. 2024;26(2):335-338. Letter to the Editor May 30, 2024 PDF
Discrepancy Between Ischemic Changes Observed on Non-Enhanced Computed Tomography and Perfusion Imaging: Implications for Decision-Making in Treatment Gabriel Broocks, Jens Fiehler, Lukas Meyer J Stroke. 2024;26(2):339-341. Letter to the Editor May 30, 2024 PDF	Sodium-Glucose Cotransporter 2 Inhibitor Improves Neurological Outcomes in Diabetic Patients With Acute Ischemic Stroke Wookjin Yang, Jeong-Min Kim, Matthew Chung, Jiyeon Ha, Dong-Wan Kang, Eung-Joon Lee, Han-Yeong Jeong, Keun-Hwa Jung, Hyunpil Sung, Jin Chul Paeng, et al. J Stroke. 2024;26(2):342-346. Letter to the Editor May 30, 2024 PDF
Cerebral Amyloid Angiopathy: An Undeniable Small Vessel Disease Litao Wang, Qiong Liu, Dongqi Yue, Jun Liu, Yi Fu J Stroke. 2024;26(2):347-347. Corrigendum May 30, 2024 PDF

	Editorial Office Department of Neurology, Asan Medical Center,Ulsan University College of Medicine 88, Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea Submission, status and progress, etc ⟫ E-mail: editor@j-stroke.org Website and system ⟫ E-mail: journal@m2community.co.kr Publishing company ⟫ E-mail: ka72sus@smileml.com
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